Funding Directory

HTA offers insights into the effectiveness and cost-effectiveness of care as delivered in typical clinical settings, accounting for the diverse range of patients eligible for the interventions being studied. Research should focus on patients with a history of essential hypertension and postural hypotension with symptoms like light-headedness or falls. Studies should consider the diverse clinical features and underlying mechanisms, particularly in underserved populations.

The intervention should prioritize hypertension control, while the comparator focuses on managing postural hypotension symptoms. Key outcomes include changes in symptoms and blood pressure control, along with hospital admissions, quality of life, and health economics. 

For more information or to apply for the funding opportunity, visit the NIHR website today!

This feasibility study will evaluate whether a randomized trial comparing hysteroscopy with polyp removal (outpatient and inpatient) to conservative management is viable for treating premenopausal women with abnormal uterine bleeding diagnosed with endometrial polyps. The intervention group will receive hysteroscopy and polyp removal, while the control group will get conservative medical management, defined and justified by applicants. Key objectives include assessing equipoise from patients and clinicians, recruitment feasibility, and the acceptability of randomization. Important outcomes to determine include health-related quality of life, potential benefits and harms, and trial delivery feasibility. Applicants should report data disaggregated by sex, gender, and other demographics. The study will be conducted in any suitable setting and include a randomized pilot phase to test recruitment, adherence, and other trial processes. Qualitative research with patients and clinicians will explore their decisions and the role of hysteroscopy versus conservative management. 

For more information or to apply for the funding opportunity, visit the NIHR website today!

This study aims to evaluate the clinical and cost effectiveness of an alternate day caplacizumab regimen compared to daily dosing in patients with immune thrombotic thrombocytopenic purpura (iTTP) who have achieved normal platelet counts. The intervention group will receive caplacizumab every other day, while the control group will continue with daily dosing, both in addition to standard care. Key outcomes include TTP relapse or exacerbation, bleeding events, and maintenance of normal platelet count. Secondary outcomes include adverse events, cost-effectiveness, and quality of life. Core Outcomes should be included unless otherwise justified, with data reported by sex and other relevant demographics. The study will be conducted in secondary care settings, featuring an internal pilot phase to assess recruitment and adherence, with clear stop/go criteria guiding progression to the full trial. Follow-up duration will be defined and justified by applicants. 

For more information or to apply for the funding opportunity, visit the NIHR  website today!

MRC CoREs should be outward facing and harness the best talent in the UK to provide a stimulating environment in which to train the next generation of researchers and technologists. MRC CoREs are expected to adopt and maintain the highest standards in the way research is conducted and openly communicated and develop and nurture career paths and a training environment which supports a positive research culture. As such, applications must emphasise the following three key principles that underpin a positive research culture: 

• Research is conducted with integrity, centred on reproducibility, responsible innovation, collaboration, interdisciplinarity and multidisciplinarity.
• Research is communicated to maximise impact, built on transparency and openness, and partnership with the public.
• Career paths and training environment, are provided to recognise a diversity of talents, skills and outputs, and embrace team science as the way of working. 

For more information or to apply for the funding opportunity, visit the UKRI website today!

Little Princess Trust (LPT) Project Grants support research into cancers affecting children and young people.

For more information or to apply for the funding opportunity, visit the Children's Cancer and Leukaemia Group website today!

Small grants, aimed at urology and cancer nursing specialists, designed to improve outcomes and patient experience for individuals with bladder cancer.

For more information or to apply for the funding opportunity, visit the Action Bladder Cancer UK website today!

The BRACE Equipment Grants support researchers at universities in South West England and South Wales undertaking research into Alzheimer's and other forms of dementia, including Lewy body dementia, frontotemporal dementia, and vascular dementia. Applications from areas related to dementia are also welcomed, including Traumatic Brain Injury, mild cognitive impairment (MCI) and young-onset dementia. Research of dementia associated with other neurological disorders, such as dementia in Parkinson’s and dementia related to Huntington’s disease, is also eligible, providing the primary research focus is on the dementia-related aspects of the disease. All researchers must intend to publish the results of their studies. 

For more information or to apply for the funding opportunity, visit the BRACE website today!

Brain Research UK project grants provide funding of up to £300,000 for projects lasting up to three years. This call particularly encourages applications from early career researchers (up to 10 years post-doc), and applications for collaborative projects (including international collaborations, if led by a UK team).

For more information or to apply for the funding opportunity, visit the Brain Research UK website today!

Funding for hypothesis-driven (clinical or non-clinical) research projects in the fields of headache and facial pain, neuro-oncology and acquired brain and spinal cord injury.

For more information or to apply for the funding opportunity, visit the Brain Research UK website today!

Blood Cancer UK offers Research Project Grants to provide support for clearly defined research proposals that aim to address key questions in the field of blood cancer in line with their strategic aims. Their research strategy 2023-2028 focuses on bringing forward the day when no one dies of blood cancer or its treatments. For this annual call applications are invited for open response-mode research projects addressing novel questions that could help reach that goal. There are no prioritised research themes for this round. 

For more information or to apply for the funding opportunity, visit the Blood Cancer UK website today!

Funding for research studies that fall within the remit of NIHR's Health and Social Care Delivery Research programme and address NICE research recommendations in order to reduce health inequalities and improve health outcomes.

For more information or to apply for the funding opportunity, visit the NIHR website today!

NIHR are looking to fund research into decarbonising the health and social care system to help reduce carbon emissions and achieve net zero. This cross-programme funding opportunity will run annually for the next 5 years.

For more information or to apply for the funding opportunity, visit the NIHR website today!

The Prevention and Population Research Programme Award is intended to support UK researchers undertaking long-term, broad and multidisciplinary projects with transformative potential in prevention and population research. It is intended to allow applicants the freedom to pursue novel research avenues. 

For more information or to apply for the funding opportunity, visit the CRUK website today!

Funding for early career and experienced researchers to develop early, novel and outside-the-box ideas and collaborations to advance the early detection and diagnosis of cancer. The CRUK Early Detection and Diagnosis Primer Awards provide seed funding to develop new relationships, ideas and lines of research, and the generation of pilot data. The aim is to encourage scientists at all career stages to engage with the early detection of cancer field and to drive innovation in how and when cancer is detected. The awards will support new and exploratory research ideas and/or pilot studies of high scientific risk and potential reward. It will support the development of new partnerships and exploration of highly novel concepts, involving researchers from any research area, including from non-traditional cancer fields. 

For more information or to apply for the funding opportunity, visit the CRUK website today!

Funding over five years to support long-term, integrated research programmes with potential to transform the early detection and diagnosis of early cancers and pre-cancerous states.  

For more information or to apply for the funding opportunity, visit the CRUK website today!

The DEBRA UK Project Grants provide funding over two to three years to support UK and international researchers conducting projects within the scope of the DEBRA UK research priorities. Projects must have clear aims and objectives to advance scientific understanding of EB and therapeutic interventions and be feasible and achievable in the stated time period. Applications will be judged on relevance to EB, scientific merit and novelty. 

For more information or to apply for the funding opportunity, visit the DEBRA UK website today!

The scheme provides long term support for broad, multidisciplinary projects in basic and translational research associated with cancer from established individuals. The CRUK research funding programme awards a wide range of fellowships and grants to support researchers, across all career stages, conducting clinical, pre-clinical, discovery and translational research to advance the detection, diagnosis, treatment, and potential cure, of all forms of cancer. 

For more information or to apply for the funding opportunity, visit the CRUK website today!

MRC welcome applications from across all areas of our remit to improve human health. This may range from basic studies with relevance to mechanisms of disease, to translational and developmental clinical research, basic studies with relevance to mechanisms of disease, to translational and developmental clinical research.

For more information or to apply for the funding opportunity, visit the UKRI website today!

The Institute's postdoctoral career development fellowships provide an opportunity for exceptional postdoctoral clinicians to consolidate their research experience. Postdoctoral clinicians can apply for funding to spend one year full-time or two years part-time working in a Crick research group, on a project agreed between the fellow and the Crick group leader. 

The aim of the scheme is to: 

• Foster long-term clinical links and collaborations.
• Provide clinicians with a postdoctoral extension of their research experience, and with scientific networking, training and career development opportunities at the Crick.
• Provide a platform from which fellows may apply for external funding such as clinician scientist fellowships, to be held at the Crick or elsewhere. 

For more information or to apply for the funding opportunity, visit the Francis Crick Institute website today!

This Funding Opportunity Announcement encourages applications that investigate the biology and underlying mechanisms of bladder cancer. Bladder cancer is a significant health problem globally. Because of the high incidence and frequent tumour recurrence, bladder cancer exacts an outsized medical burden. While recent progress has been made in the molecular profiling of bladder cancers and identification of mutated genes, relatively little is known regarding the molecular mechanisms driving initiation, progression and malignancy of bladder cancer. Furthermore, understanding of the biological processes of the normal bladder at the molecular, cell and organ levels is limited. 

Fundamental knowledge of how molecular and cellular functions of the bladder are altered in cancer will aid understanding of bladder cancer biology and contribute to the future development of new interventions. 

For more information or to apply for the funding opportunity, visit the NIHR website today!

This Funding Opportunity Announcement (FOA) supports discrete, well-defined projects in any area of cancer research using the NIH R03 small grant mechanism. The NIH R03 small grant mechanism supports discrete, well-defined projects that realistically can be completed in two years and that require limited levels of funding. Examples of the types of projects that the R03 grant mechanism include, but are not limited to, the following: 

• Pilot or feasibility studies.
• Secondary analysis of existing data.
• Small, self-contained research projects.
• Development of research methodology.
• Development of new research technology.

For more information or to apply for the funding opportunity, visit the NIH website today!

This Notice of Funding Opportunity (NOFO) invites mechanistic research that aims to understand how and why expectancy effects occur in a cancer context, elucidate their role in cancer symptom management, and identify patients, symptoms, cancer sites and contexts in which expectancy effects can be leveraged to improve cancer outcomes. Expectancies are defined in this context as beliefs about future outcomes, including one's response to cancer or cancer treatment. Expectancies can be evoked by social, psychological, environmental and systemic factors. Expectancy effects are the cognitive, behavioural and biological outcomes caused by expectancies. Expectancy effects can be generated by expectancies held by patients, clinicians, family members, caregivers and/or dyadic/social networks.

For more information or to apply for the funding opportunity, visit the NIH website today!

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) is inviting research projects that implement early phase (Phase 0, I and II) investigator-initiated clinical trials focused on cancer-targeted diagnostic and therapeutic interventions of direct relevance to the research mission of NCI's Division of Cancer Treatment and Diagnosis (DCTD) and Office of HIV and AIDS Malignancies (OHAM). 

The proposed project must involve at least one clinical trial related to the scientific interests of one or more of the following research programs: Cancer Therapy Evaluation Program, Cancer Imaging Program, Cancer Diagnosis Program, Radiation Research Program, Complementary and Alternative Medicine Program, and/or the HIV and AIDS Malignancies Research Programs. 

For more information or to apply for the funding opportunity, visit the NIH website today!